The La Roche-Posay Adapalene Acne Gel is their flagship direct acne treatment product, with 0.1% Adapalene (a topical retinoid). Used to prevent and cure acne, breakouts, pimples, maskne, whiteheads, blackheads and other related issues. The prescription strength La Roche-Posay Adapalene Acne Treatment Gel with 0.1% Adapalene is one of their newer acne products. One of the most acclaimed, non-prescription, acne treatment products anywhere in the world, it prevents and treats breakouts, blackheads, whiteheads, blemishes and clogged pores. Adapalene gel is the first new over-the-counter active ingredient for the treatment of acne approved by the FDA in over 30 years.